Gene description for EGFR |
Gene name |
epidermal growth factor receptor |
Gene symbol |
EGFR |
Other names/aliases |
ERBB ERBB1 ERRP HER1 NISBD2 PIG61 mENA |
Species |
Homo sapiens |
Experiment description of studies that identified EGFR in Lung cancer cells |
1
|
Experiment ID | 282 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
19234131
|
Organism | Homo sapiens |
Experiment description | Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR |
Authors | Al-Nedawi K, Meehan B, Kerbel RS, Allison AC, Rak J |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2009 |
Sample | Lung cancer cells |
Sample name | A549 |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 612 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | NCI-H226 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 1583 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
33686255
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicle drug occupancy enables real-time monitoring of targeted cancer therapy. |
Authors | Pan S, Zhang Y, Natalia A, Lim CZJ, Ho NRY, Chowbay B, Loh TP, Tam JKC, Shao H. |
Journal name |
Nat Nanotechnol
|
Publication year | 2021 |
Sample | Lung cancer cells |
Sample name | H3255 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 3395 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Flow cytometry
|
PubMed ID |
31792209
|
Organism | Homo sapiens |
Experiment description | Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles |
Authors | Xie X, Nie H, Zhou Y, Lian S, Mei H, Lu Y, Dong H, Li F, Li T, Li B, Wang J, Lin M, Wang C, Shao J, Gao Y, Chen J, Xie F, Jia L. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Lung cancer cells |
Sample name | A549 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Flow cytometry |
EV-TRACK |
-
|
|
|